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sigO [2017-8-11 16:0:3]
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sigO [2017-8-11 16:0:3]

RNA polymerase sigma factor SigO (with RsoA)
locus
BSU33230
pI
9.78
mw
22.54 kDa
protein length
177 aa Sequence Blast
gene length
531 bp Sequence Blast
function
RNA polymerase sigma factor
product
co-sigma factor with RsoA
essential
no
synonyms
yvrI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.3|Acid stress proteins (controlled by YvrI-YvrHa)]

    • Gene

    Coordinates
    3,409,462 → 3,409,992

    The protein

    [SW|Domains]

  • contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors [Pubmed|19940246]

    • Expression and Regulation

    Operons

    genes
    [gene|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]-[gene|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]
    description
    [Pubmed|19047353]

    sigma factors

  • [protein|6359025A73C0BD313F5BCC6F56FE88B820902AAA|SigO]: sigma factor, [Pubmed|19047353], in [regulon|6359025A73C0BD313F5BCC6F56FE88B820902AAA|SigO regulon]
  • [protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|RsoA]: sigma factor, in [regulon|AE8D4F07EFB17DA727D80229C3E72075928AA352|RsoA regulon]

    • regulatory mechanism

  • [protein|7098319D8E88FDC2A629A3F4A21507FD7A649385|YvrHb]: activation, [Pubmed|16306698], in [regulon|7098319D8E88FDC2A629A3F4A21507FD7A649385|YvrHb regulon]

    • regulation

  • induced by acidic growth conditions [Pubmed|19047353]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B052 (yvrI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1051 NBRP B. subtilis, Japan]

    • Labs working on this gene/protein

  • [SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]

    • References

  • 18573182,19047353,26651345,16306698,19940246,26367498,26400263,27558998